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Science Delivers - For Keeps |
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Unlike religion, politics or commerce |
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"Some people think science is a matter of idle
curiosity. A cure for this nonsense is a few hours of observation in a
hospital intensive care ward. And if one happens to be a patient in such
circumstances, even astrophysics is suddenly relevant"
- Anonymous
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"While everyone is entitled to
their opinions, when dealing with detailed technical matters of science or
medicine or any subject that requires enormous qualifications and
experience, the notion that all opinions have equal validity is simply
downright wrong. If you want real information on the safety of heart surgery
procedures, do you follow the advice of a qualified heart surgeon or the
local butcher? If you want advice on flying a jumbo jet, do you ask the
local bus driver or a pilot with 10,000 hours of experience flying jumbo
jets? And if you want advice on how to captain a supertanker, do you ask a
person whose experience is limited to rowing a dinghy? Mistakes by surgeons
are not uncommon, 70% of air crashes result from pilot error, and
occasionally supertankers hit the rocks. But relying on rank amateurs
instead of professionals would guarantee instant catastrophe. Many branches
of science are very complex. However, being a scientist isn't enough, of
course, as being a scientist doesn't qualify you to advise on any subject
except your specialty. To provide advice that can lead to sensible policy
requires not only a thorough understanding of the workings and literature of
the particular scientific area but many decades of experience in that field."
- Redefining “Natural” in Agriculture, Tony
Trewavas, 2008
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Who Loves Designer Vaginas?
Science and nature are mocking America's fickle God. Please,
no screaming.
Mark Morford
SF Gate Columnist
Wed June 20, 2007
What are you gonna do about it?
What are you gonna do about the fact that Mother Nature once again appears
to be thwarting and mocking and then grinning like a wicked divine trickster
at every cute rigid godly idea of how humans and animals are supposed to
move and hump and lick and behave, as loosely and, yes, rather bitterly
delineated in the Bible and by the Bush administration and Focus on the
Family and every other uptight sexually confounded person you have ever
known, et al. and ad nauseam?
What, furthermore, are you gonna do about human knowledge? About how science
insists on marching hell-bent forward with such astonishing speed and with
such incredible dexterity toward some glorious otherworldly nightmare
dreamscape of anima manipulation, a land where we can effortlessly
rescramble our genetic code and reconfigure this none-too-solid flesh as we
"play God" in so many bewildering ways the Christian right can't even figure
out where to aim its hollow, horrified indignation?
Here is the thing you must know: It is all changing with incredible,
butt-tingling speed. It is all fast becoming more than we ever imagined,
with ramifications we are only beginning to fully taste. There is no
stopping it. There is little that can slow it down. There is only the
single, looming question: How will you respond? Will you recoil and gag and
spit, or will you gurgle and swallow and smile?
Example: We are on the cusp of being able choose, should you so desire, the
exact size and length and speed and eye color and specific pleasing fur
markings of ... your dog. And your cat. And your baby (well, minus the fur).
And by the way, we have also invented new drugs to eliminate menstruation
and we can now grow designer vaginas in the lab and plastic surgery is more
common than bad sacrum tattoos and it's becoming increasingly obvious that
males of many species -- including our own -- are largely unnecessary for
procreation (but not, say, parallel parking, the lifting of heavy things or
buying you a nice postcoital breakfast).
Fascinating, that last thing. Have you heard? Scientists are discovering
more and more creatures, from sharks to bees to ants to turkeys to Komodo
dragons to turtles to sea bass, that can reproduce via parthenogenesis
(i.e., virgin birth; i.e., no father) either by actually switching sexes so
as to fertilize themselves, or via storing sperm for years for later use, or
because they're hermaphrodites, or by way of undertaking all manner of
clever unholy gender trickery so as to circumvent their own extinction and
confound creationists and ensure that all humans everywhere will continue to
look around and blink furiously and go, Wait wait wait, didn't we have some
of this figured out already? What the hell happened?
Wait, did I say designer vaginas? Indeed I did. Doctors can now grow new
vaginal tissue in a lab, from the original stem cells, for eventual
replanting (not to be confused with the hot trend in cosmetic vaginoplasty,
by the way, which is an entirely different fascination and has to do with
reshaping the labia for improved aesthetics and, you know, functionality.
God bless America).
Fabulous news for victims of birth defects and cancer and rare vaginal
disorders? You bet. Intriguing implications for all sorts of cosmetic
applications, not to mention what it might mean for transsexuals, not to
mention how close we are to doing the same thing with other organs -- and
even, eventually, entire limbs? One guess.
It is, we can all agree, a lot to take in. It is a great deal to attempt to
process in one tiny and oh-so-fleeting lifetime. The notion of human
eugenics alone is, for many, overwhelming enough, the idea that new parents
will soon have some sort of checklist at the gynecologist's office wherein,
when docs go in to tweak your fetus' DNA to eliminate diseases, you can also
easily choose not only its sex, but also the skin tone and hair color and
eye tint and muscle dexterity and 0-60 acceleration and number of cupholders
and overall genetic propensity toward an IQ that may or may not lead to
voting for aw-shucks warmongering neocon imbecile politicians. Neat! Or, you
know, not.
They are, quite obviously, the sort of advances that open so many cans of
ethical and spiritual worms it shakes us to the very core of what we
believe, of who we think we are and where we fit in and What It All Means.
You know, the good questions.
At the same time, it's really nothing new. It's little different than
previous periods of explosive growth in human knowledge that both titillated
and terrified the populace, such as, say, when Galileo pointed out (much to
the church's quivering rage) that not only is man's little spinning blue
spaceship not at the center of the universe, but we're actually so far out
on the fringes, so minute and insignificant in our Copernican swirlings that
we're really nothing more than a wisp of belly-button lint in the giant
laundry hamper of the gods. Talk about your existential angst.
Hence, religion. This (at least partially) explains why so many are so eager
to cling to religious dogma, to some sort of immovable, reliable framework
of understanding, something that can help make sense of it all, even if
making sense of it all involves shutting off your brain and killing your
divine intuition and soaking up giant gobs of blind faith so you don't have
to actually swim in those bloody murky confusing pools of ethics and meaning
and actually thinking for yourself. Mmm, numb groupthink. It's what's for
dinner.
There are only two real options. One is to hold tight to the leaky life raft
of inflexible ideology (hello, organized religion), to rules and laws and
codes of conduct written by the fearful, for the fearful, to live in
constant low-level dread of all the extraordinary changes and radical
rethinkings of what it means to be human or animal or male or female or
hetero or homo or any other swell little label you thought was solid and
trustworthy but which is increasingly proven to be blurry and unpredictable
and just a little dangerous.
There is another option. You can choose nimbleness, lightness, a sly and
knowing grin to go with your wine and your vibrator and your never-ending
thirst for more and deeper information. It's possible.
You can refuse to let your brain, your soul lock down into one way of
looking at the world as you see all the science and genetic manipulation and
designer vaginas, all the insane, incredible possibility as merely more
evidence that we are, in the end, just one big karmic science experiment.
Is this latter choice frustrating and brutally difficult and will it
challenge every notion of self you hold dear? Hell yes. Is it the only way
to enjoy this bizarre circus of a planet without grabbing a gun and cowering
in the corner with your homophobia and your flag and your Army of Christ
brochure, dead certain the terrorists and gays and hippies are coming to eat
your soul for breakfast? Well, probably.
Because, baby, the changes are coming, harder and faster than ever, with all
sorts of juicy, terrifying, delightful implications. Really now, what are
you gonna do about it?
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'Keats claimed physics
destroyed beauty. Keats was being a prat'
Britain produced some of the world's great physicists but few
schoolchildren want to study the subject now. Simon Singh explains why we
should worry
Simon Singh
Tuesday November 22, 2005
Guardian
We are nearing the end of
the "World Year of Physics", otherwise known as Einstein Year, as it is the
centenary of his annus mirabilis in which he made three incredible
breakthroughs, including special relativity. In fact, it was 100 years ago
yesterday that he published the most famous equation in the history of
physics: E=mc2.
But instead of celebrating, physicists are in mourning after a report
showed a dramatic decline in the number of pupils studying physics at
school. The number taking A-level physics has dropped by 38% over the past
15 years, a catastrophic meltdown that is set to continue over the next few
years. The report warns that a shortage of physics teachers and a lack of
interest from pupils could mean the end of physics in state schools.
Thereafter, physics would be restricted to only those students who could
afford to go to posh schools.
Britain was the home of Isaac Newton, Michael Faraday and Paul Dirac, and
Brits made world-class contributions to understanding gravity, quantum
physics and electromagnetism - and yet the British physicist is now facing
extinction. But so what? Physicists are not as cuddly as pandas, so who
cares if we disappear?
You should care, and this is why. First, physicists reveal the beauty of
the universe. E=mc2 provides us with an incredible insight into how the
universe works, showing us that energy (E) and mass (m) can be converted
into each other, so that a tiny amount of mass can be destroyed to create a
vast amount of energy. That is how the Sun shines. Four million tonnes of
the Sun literally vanishes every second, only to reappear in the form of
sunshine - energy that lights up our lives.
John Keats talked of "unweaving the rainbow", suggesting that Newton
destroyed the beauty of nature by analysing light with a prism and splitting
it into different colours. Keats was being a prat. Physicists also smile
when we see rainbows, but our emotional reaction is doubled by our
understanding of the deep physics relating to the prismatic effects of
raindrops. Similarly, physicists appreciate sunsets more than anybody else,
because we can enjoy the myriad colours and at the same time grasp the
nuclear physics that created the energy that created the photons that
travelled for millions of years to the surface of the Sun, which then
travelled eight minutes through space to Earth, which were then scattered by
the atmosphere to create the colourful sunset. Understanding physics only
enhances the beauty of nature.
If you want a concrete return, then physics can deliver that too. E=mc2
underpins the nuclear power industry, which could provide more energy in the
future. If nuclear power replaced fossil fuels, we would pump less carbon
into the atmosphere and thereby halt global warming. If, instead, you want
clean energy via solar cells or wind turbines, then an understanding of
solid state physics or the physics of fluids will get you several steps
closer to an economically viable solution. Either way, physics provides the
best hope of saving the planet.
Also, it should not be forgotten that A-level physicists have a direct
impact on the economy, because some of us become the inventors, innovators
and engineers that create high-quality jobs and major exports. The people
behind Google and Microsoft and Apple did physics at high school, as opposed
to majoring in psychology or media studies.
So, without British physicists, our country will not win any more Nobel
prizes in physics, we will not do our part in fixing global warming - and UK
plc will go down the drain. And yet nobody in power really cares. Physics in
British schools has been going downhill for a couple of decades, but both
Labour and Conservative governments seem to have taken no notice. After all,
nobody is going to die because A-level physics is going out of fashion.
There are no photo opportunities in being seen with a physicist.
Personally, the desperate state of British physics education was brought
home to me when I reflected on why my parents migrated to this country in
1950. They came here so that their children had the guarantee of a good
education. However, today India produces more mathematicians than the whole
of the European Union.
A budding boffin in Bangalore probably stands more chance of having good
mathematics and physics teachers than the equivalent bright young spark
condemned to a British science education. A British politician in 1950 would
have laughed at the thought of Indian schools ever being better than British
schools, but last year's Physics Olympiad shows how things have changed. In
this international competition for schools students, India won two gold
medals, two silvers and a bronze, whereas Britain won only two bronzes.
With Britain's negligent attitude to physics education, we do not deserve
to be celebrating the centenary of Einstein's annus mirabilis. Instead,
perhaps we should be marking 2005 as the 50th anniversary of his death,
which would be in keeping with the moribund status of A-level physics
Simon Singh has a PhD in particle physics. He is the author of
Big Bang, a history of cosmology.
Do you know your Newton from your neutrons?
1. A metal plate is heated to 200C with a bunsen burner. It
subsequently cools by emitting what kind of radiation?
a) Ultraviolet waves b) Gamma rays c) Infrared rays d) Radio waves
2. You're in the back of a stationary car with a helium balloon. When
the car accelerates, which way does the balloon move?
a) Forwards b) Backwards c) Up d) It doesn't move
3. What two properties of a particle does Heisenberg's uncertainty
principle say you can't measure at the same time?
a) Energy and mass b) Position and momentum c) Position and mass d) Momentum
and velocity
4. A skater is spinning on a spot with her arms outstretched. What
happens when she pulls her arms in?
a) Nothing b) She changes direction c) She spins more slowly d) She spins
more quickly
5. A big wooden ball and a small ball bearing sit at the top of a
slope. When they are released, which reaches the bottom first?
a) The wooden ball b) The ball bearing c) They both get there at the same
time d) Depends on the masses of the balls and the angle of the slope
6. If the Sun were to disappear right now, how long would it be before
we noticed?
a) Straight away b) About 8 minutes c) Just over an hour d) Almost a day
Answers: 1c, 2a, 3b, 4d, 5c, 6b
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New Tools to Help Patients Reclaim Damaged Senses
by Sandra Blakeslee
The Times
November 23, 2004
Cheryl Schiltz vividly recalls the morning she became a wobbler. Seven years
ago, recovering from an infection after surgery with the aid of a common
antibiotic, she climbed out of bed feeling pretty good.
"Then I literally fell to the floor," she said recently. "The whole world
started wobbling. When I turned my head, the room tilted. My vision blurred.
Even the air felt heavy."
The antibiotic, Ms. Schiltz learned, had damaged her vestibular system, the
part of the brain that provides visual and gravitational stability. She was
forced to quit her job and stay home, clinging to the walls to keep from
toppling over.
But three years ago, Ms. Schiltz volunteered for an experimental treatment -
a fat strip of tape, placed on her tongue, with an array of 144
microelectrodes about the size of a postage stamp. The strip was wired to a
kind of carpenter's level, which was mounted on a hard hat that she placed
on her head. The level determined her spatial coordinates and sent the
information as tiny pulses to her tongue.
The apparatus, called a BrainPort, worked beautifully. By "buzzing" her
tongue once a day for 20 minutes, keeping the pulses centered, she regained
normal vestibular function and was able to balance.
Ms. Schiltz and other patients like her are the beneficiaries of an
astonishing new technology that allows one set of sensory information to
substitute for another in the brain.
Using novel electronic aids, vision can be represented on the skin, tongue
or through the ears. If the sense of touch is gone from one part of the
body, it can be routed to an area where touch sensations are intact. Pilots
confused by foggy conditions, in which the horizon disappears, can right
their aircraft by monitoring sensations on the tongue or trunk. Surgeons can
feel on their tongues the tip of a probe inside a patient's body, enabling
precise movements.
Sensory substitution is not new. Touch substitutes for vision when people
read Braille. By tapping a cane, a blind person perceives a step, a curb or
a puddle of water but is not aware of any sensation in the hand; feeling is
experienced at the tip of the cane.
But the technology for swapping sensory information is largely the effort of
Dr. Paul Bach-y-Rita, a neuroscientist in the University of Wisconsin
Medical School's orthopedics and rehabilitation department. More than 30
years ago, Dr. Bach-y-Rita developed the first sensory substitution device,
routing visual images, via a head-mounted camera, to electrodes taped to the
skin on people's backs. The subjects, he found, could "see" large objects
and flickering candles with their backs. The tongue, sensitive and easy to
reach, turned out to be an even better place to deliver substitute senses,
Dr. Bach-y-Rita said.
Until recently sensory substitution was confined to the laboratory. But
electronic miniaturization and more powerful computer algorithms are making
the technology less cumbersome. Next month, the first fully portable device
will be tested in Dr. Bach-y-Rita's lab.
The BrainPort is nearing commercialization. Two years ago, the University of
Wisconsin patented the concept and exclusively licensed it to Wicab Inc., a
company formed by Dr. Bach-y-Rita to develop and market BrainPort devices.
Robert Beckman, the company president, said units should be available a year
from now.
Meanwhile, a handful of clinicians around the world who are using the
BrainPort on an experimental basis are effusive about its promise.
"I have never seen any other device do what this one does," said Dr. F. Owen
Black, an expert on vestibular disorders at the Legacy Clinical Research and
Technology Center in Portland, Ore. "Our patients are begging us to continue
using the device."
Dr. Maurice Ptito, a neuroscientist at University of Montreal School of
Optometry, is conducting brain imaging experiments to explore how BrainPort
works.
Dr. Eliana Sampaio, a neuroscientist at the National Conservatory of Arts
and Mtiers in Paris, is using the BrainPort to study brain plasticity.
Sensory substitution is based on the idea that all sensory information
entering the brain consists of patterns carried by nerve fibers.
In vision, images of the world pass through the retina and are converted
into impulses that travel up the optic nerve into the brain. In hearing,
sounds pass through the ear and are converted into patterns carried by the
auditory nerve into the brain. In touch, nerve endings on skin translate
touch sensations into patterns carried into the brain.
These patterns travel to special sensory regions where they are interpreted,
with the help of memory, into seeing, hearing and touch. Patterns are also
seamlessly combined so that one can see, hear and feel things
simultaneously.
"We see with the brain, not with the eyes," Dr. Bach-y-Rita said. "You
can lose your retina but you do not lose the ability to see as long as your
brain is intact."
Most important, the brain does not seem to care if patterns come from the
eye, ear or skin. Given the proper context, it will interpret and understand
them."For me, it happened automatically, within a few minutes," said
Erik Weihenmayer, who has been blind since he was 13.
Mr. Weihenmayer, a 35-year-old adventurer who climbed to the summit of Mount
Everest two years ago, recently tried another version of the BrainPort, a
hard hat carrying a small video camera. Visual information from the camera
was translated into pulses that reached his tongue.
He found doorways, caught balls rolling toward him and with his small
daughter played a game of rock, paper and scissors for the first time in
more than 20 years. Mr. Weihenmayer said that, with practice, the
substituted sense gets better, "as if the brain were rewiring itself."
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Ms. Schiltz, too, whose vestibular system was damaged by gentamicin, an
inexpensive generic antibiotic used for Gram-negative infections, said that
the first few times she used the BrainPort she felt tiny impulses on her
tongue but still could not maintain her balance. But one day, after a full
20-minute session with the BrainPort, Ms. Schiltz opened her eyes and felt
that something was different. She tilted her head back. The room did not
move. "I went running out the door," she recalled. "I danced in the parking
lot. I was completely normal. For a whole hour." Then, she said, the problem
returned.
She tried more sessions. Soon her balance was restored for three hours, then
half a day. Now working with the BrainPort team at the University of
Wisconsin, Ms. Schiltz wears the tongue unit each morning. Her balance
problems are gone as long as she keeps to the regimen.
How the device produces a lasting effect is being investigated. The
vestibular system instructs the brain about changes in head movement with
respect to the pull of gravity. Dr. Bach-y-Rita speculated that in some
patients, a tiny amount of vestibular tissue might survive and be
reactivated by the BrainPort.
Dr. Black said he had seen the same residual effect in his own pilot study.
"It decays in hours to days," he said, "but is very encouraging."
Blind people who have used the device do not report lasting effects. But
they are amazed by what they can see. Mr. Weihenmayer said the device at
first felt like candy pop rocks on his tongue. But that sensation quickly
gave way to perceptions of size, movement and recognition.
Mr. Weihenmayer said that on several occasions he was able to find his wife,
who was standing still in an outdoor park, but he admitted that he also once
confused her with a tree. Another time, he walked down a sidewalk and almost
went off a bridge.
Nevertheless, he is enthusiastic about the future of the device. Mr.
Weihenmayer likes to paraglide, and he sees the BrainPort as a way to
deliver sonar information to his tongue about how far he is from the ground.
Dr. Ptito is scanning the brains of congenitally blind people who, wearing
the BrainPort, have learned to make out the shapes, learned from Braille, of
capital letters like T, B or E. The first few times they wore the device, he
said, their visual areas remained dark and inactive - not surprising since
they had been blind since birth. But after training, he said, their visual
areas lighted up when they used the tongue device. The study has been
accepted for publication in the journal Brain.
Dr. Ptito says he would like to see if he could teach his subjects how to
read drifting letters like those in advertising displays. Not seeing motion
is a big problem for the blind, he said.
In another approach, Dr. Peter Meijer, a Dutch scientist working
independently, has developed a system for blind people to see with their
ears. A small device converts signals from a video camera into sound
patterns delivered by stereo headset to the ears. Changes in frequency
connote up or down. Changes in pixel brightness are sensed as louder or
softer sounds.
Dr. Yuri Danilov, a neuroscientist and engineer who works with Dr.
Bach-y-Rita, said the research team had thought of dozens of applications
for the BrainPort, which he called a "USB port to the brain."
In one experiment, a leprosy patient who had lost the ability to experience
touch with his fingers was outfitted with a glove containing contact
sensors. These were coupled to skin on his forehead. Soon he experienced the
data coming from the glove on his forehead, as if the feelings originated in
his fingertips. He said he cried when he could touch and feel his wife's
face.
The federal government has also shown interest in sensory substitution
technology. The Navy is exploring the use of a tongue device to help divers
find their way in dark waters at night, said Dr. Anil Raj, director of the
Institute for Human and Machine Cognition at the University of West Florida
in Pensacola.
The sensors detect water surges, informing Navy Seals if they are following
the correct course. The Army is thinking about sending infrared signals from
night goggles directly to the tongue, Dr. Raj said.
In another application, student pilots have been fitted with body sensors
attached to aircraft instruments. When the airplane starts to pitch or
change altitude, they can feel the movements on their chests.
Sensory substitution technology may eventually help millions of people
overcome their sensory disabilities. But the devices may also have more
frivolous uses: in video games, for example.
Dr. Raj said the tongue unit had already been tried out in a game that
involved shooting villains. "In two minutes you stop feeling the buzz on
your tongue and get a visual representation of the bad guy," he said. "You
feel like you have X-ray vision. Unfortunately it makes the game boring."
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Space science joins battle against cancer
ESA research can lead to better medical equipment
19 November 2003
Ground-breaking techniques which will be used to find tiny planets orbiting
stars outside our Solar System are already being developed to help
scientists detect cells in the early stages of cancer.
The enormous amount of light emitted by a star makes it extremely difficult
to spot a planet in orbit around it. By using a technique that
combines signals from two or more telescopes, ESA
astronomers are able to create an artificial solar
eclipse, 'neutralising' the effects of the bright starlight
so that the fainter light from a planet can be detected.
Darwin's flotilla of telescopes look for Earth-like planets
European space scientists have now developed the technique even further so
that they can even study the atmospheres of such planets. ESA's
Darwin mission, which will study up to 1000 nearby stars, will be one
of the first to use this technique to take us a step further towards
answering the question 'Are we alone in the Universe?'
But scientists in the Netherlands are excited about another application for
this revolutionary technique. The national research organisation TNO/TPD
has
developed this imaging technology for medical use.
Using this technique, scientists can now obtain images of skin or tissue
that are of much higher resolution than currently available. The
technique is already being used to study changes
in blood vessels and the retina, but it could be
used as an early detection method for cancerous growths.
This will not be the first time that space technology has been used in the
fight against cancer. A computer program originally developed by
European scientists to find the sources of X-rays
in deep space has been modified to produce a
computer-aided early recognition system for skin melanomas.
The original software was used to block out background 'noise' in signals
coming from space in order to detect weaker signals emitted from the
remnants of supernova explosions.
Here on Earth, a sample of the surface of skin can be scanned and then
magnified 10 times. The computer program then picks out the tiniest
variations in colour, allowing doctors to see much more clearly
whether there are any irregularities in cell
growth, associated with malignant melanomas. |
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